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Arancaytar
Law Bringer
Member # 2984
 written Wednesday, August 31 2005 19:49 Profile Homepage #25
Oh. For some reason I have always confused Diethylstilbestrol with Thalidomide.

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Posts: 8752 | Registered: Wednesday, May 14 2003 07:00
Thuryl
...b10010b...
Member # 869
 written Wednesday, August 31 2005 21:43 Profile Homepage #26
Probably because they both cause birth defects? :P

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Posts: 9973 | Registered: Saturday, March 30 2002 08:00
JadeWolf
Infiltrator
Member # 5567
 written Wednesday, August 31 2005 22:10 Profile Homepage #27
Congratulations Thuryl!
I can't even pronounce your current moniker [copy][paste] diethylstilbestrol [/paste][/copy] . Every time I try to, it comes out as "dyithyllitbestrol" or some like it.

EDIT: Did it!

[ Wednesday, August 31, 2005 22:14: Message edited by: JadeWolf ]

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Posts: 576 | Registered: Wednesday, March 2 2005 08:00
Icshi
Mongolian Barbeque
Member # 1528
 written Wednesday, August 31 2005 22:21 Profile #28
quote:
Originally written by Diethylstilbestrol:

Probably because they both cause birth defects? :P
If that's the case, then you might as well go ahead and equate it with unregulated breeding. :P

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Posts: 907 | Registered: Monday, July 15 2002 07:00
Arancaytar
Law Bringer
Member # 2984
 written Thursday, September 1 2005 01:27 Profile Homepage #29
Thalidomide was unproportionally less long-lasting in the consequences though. For one, the deformations were not hereditary afaik, and for the other, they came to light immediately and not after the medication had already been used for some 30 years.

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"Polaris leers down from the black vault, winking hideously like an insane watching eye which strives to convey some strange message, yet recalls nothing save that it once had a message to convey." --- HP Lovecraft.
"I single Aran out due to his nasty temperament, and his superior intellect." --- SupaNik
Posts: 8752 | Registered: Wednesday, May 14 2003 07:00
Thuryl
...b10010b...
Member # 869
 written Thursday, September 1 2005 01:52 Profile Homepage #30
The problems caused by DES aren't hereditary as such either. The reason a third generation was affected was that the abnormalities in the reproductive tracts of women whose mothers had been treated with DES led to problems with the foetal development of their own children. Since those problems (mostly premature births and neurological abnormalities) don't generally affect the reproductive system of the child, it's not expected that the fourth generation will experience any problems.

[ Thursday, September 01, 2005 01:53: Message edited by: Diethylstilbestrol ]

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Posts: 9973 | Registered: Saturday, March 30 2002 08:00
Drew
By Committee
Member # 4233
 written Thursday, September 1 2005 03:48 Profile #31
As opposed to the problems a mentally handicapped person with stunted, misformed, or altogether missing limbs would have getting to the child-birthing point.

Granted, the range of impacts Thalidomide had on a fetuses was large - not all of them had deformation in all limbs or were necessarily mentally handicapped, but yeesh! it was pretty bad stuff.

Interestingly, it's not entirely off the market - it's still a valid treatment for the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL), a particularly unhappy sort of lesions. It is way, way, way controlled though regarding to whom it can be prescribed, and physicians are required to educate their patients thoroughly regarding the risks.

[ Thursday, September 01, 2005 03:57: Message edited by: Drew ]
Posts: 2242 | Registered: Saturday, April 10 2004 07:00
Arancaytar
Law Bringer
Member # 2984
 written Thursday, September 1 2005 05:33 Profile Homepage #32
quote:
Originally written by Drew:

Interestingly, it's not entirely off the market - it's still a valid treatment for the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL), a particularly unhappy sort of lesions. It is way, way, way controlled though regarding to whom it can be prescribed, and physicians are required to educate their patients thoroughly regarding the risks.
Since the teratogenic effect is pretty much limited to pregnant women, it's not even that harmful a medication for others - although it is apparently mildly carcinogenic.

[ Thursday, September 01, 2005 05:34: Message edited by: Arancaytar ]

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The Encyclopaedia Ermariana <-- Now a Wiki!
"Polaris leers down from the black vault, winking hideously like an insane watching eye which strives to convey some strange message, yet recalls nothing save that it once had a message to convey." --- HP Lovecraft.
"I single Aran out due to his nasty temperament, and his superior intellect." --- SupaNik
Posts: 8752 | Registered: Wednesday, May 14 2003 07:00
Drew
By Committee
Member # 4233
 written Thursday, September 1 2005 05:48 Profile #33
It does have a pretty enormous "black box" warning in its US labeling though, which spells out lots of unpleasantness, and also, as a rule, prevents it from being advertised at all.
Posts: 2242 | Registered: Saturday, April 10 2004 07:00
Archmage Alex
Skip to My Lou
Member # 40
 written Thursday, September 1 2005 06:40 Profile Homepage #34
IMAGE(http://i11.photobucket.com/albums/a181/Alexsticks/diethylstilbestrol.gif)

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Posts: 1629 | Registered: Wednesday, October 3 2001 07:00
Nikki.
Shaper
Member # 3442
 written Thursday, September 1 2005 06:49 Profile Homepage #35
quote:
Originally written by Archmage Alex:

IMAGE(http://i11.photobucket.com/albums/a181/Alexsticks/diethylstilbestrol.gif)
Give that man a medal.

And Thyurl...

quote:
In the 1950s it was found not to significantly reduce the risk of miscarriage or premature birth, but continued to be prescribed for another two decades.
Why? Did they not know about the side-effects?

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Posts: 2864 | Registered: Monday, September 8 2003 07:00
Thuryl
...b10010b...
Member # 869
 written Thursday, September 1 2005 13:56 Profile Homepage #36
quote:
Originally written by SupaNik:

quote:
In the 1950s it was found not to significantly reduce the risk of miscarriage or premature birth, but continued to be prescribed for another two decades.
Why? Did they not know about the side-effects?
Since the side effects only affected a small proportion of children whose mothers were given DES, it took a while for them to become completely obvious to the point where continuing to sell the drug was likely to get people sued.

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Posts: 9973 | Registered: Saturday, March 30 2002 08:00
Sir David
Fire! Fire! Fire! Fire!
Member # 919
 written Thursday, September 1 2005 20:23 Profile #37
So much for daily name changes...

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In case of emergency, break glass.
Posts: 3351 | Registered: Saturday, April 6 2002 08:00
Ash Lael
E Equals MC What!!!!
Member # 5491
 written Thursday, September 1 2005 20:27 Profile Homepage #38
Australian days do not correspond exactly with American days.

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Posts: 1861 | Registered: Friday, February 11 2005 08:00
Thuryl
...b10010b...
Member # 869
 written Thursday, September 1 2005 20:28 Profile Homepage #39
Time zones, remember? I was changing around 12-1 pm my time the past two days. It's now 3:30 pm as I post this, on account of the fact that I only just got home from university. Still once a day. :P

My current name, Monkey Glands, refers, of course, to the early-20th-century fad for surgically implanting slices of monkey testicle in older men, in the hope of restoring their youth and virility. I hope it comes as no surprise to anybody that this didn't actually work, although it was very popular in its time.

(Actually, even going by forum time, this was still posted the day after the previous name change.)

[ Sunday, September 04, 2005 23:45: Message edited by: Fenfluramine ]

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Posts: 9973 | Registered: Saturday, March 30 2002 08:00
Jumpin Salmon
? Man, ? Amazing
Member # 5755
 written Thursday, September 1 2005 21:00 Profile #40
Okay, I'm curious where this fad took place. Cuz here in the States we had fads related to being young, boozing, spawning, gambling (NYSE), starving, and sick with flu-like symptoms. I don't remember the testicles being part of any of those things. And where did the testicles come from? I mean, I know where testicles come from, but where did the monkeys come from that donated their testicles? Also, were the testicles treated in any way prior to insertion, or were they raw?

*this message sponsored by viagra*
Posts: 4114 | Registered: Monday, April 25 2005 07:00
Ash Lael
E Equals MC What!!!!
Member # 5491
 written Thursday, September 1 2005 21:03 Profile Homepage #41
In case you didn't notice, it was a fad among older men.

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Sex is easier than love.
Posts: 1861 | Registered: Friday, February 11 2005 08:00
Icshi
Mongolian Barbeque
Member # 1528
 written Thursday, September 1 2005 21:08 Profile #42
I expect this produced even worse birth defects than Diethylstilbestrol.

So when the wife was complaining that the children were behaving like a bunch of howler monkeys...

[ Thursday, September 01, 2005 21:09: Message edited by: Icshi ]

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Posts: 907 | Registered: Monday, July 15 2002 07:00
Skribbane Freak
Warrior
Member # 5802
 written Thursday, September 1 2005 21:09 Profile #43
Congrads Thuryl! ^_^

EDIT: misspelt Thuryl

[ Thursday, September 01, 2005 21:11: Message edited by: Grape slime ]

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polaris c'mon you know you want to
Avernum4 Averforge
Posts: 156 | Registered: Wednesday, May 11 2005 07:00
Arancaytar
Law Bringer
Member # 2984
 written Thursday, September 1 2005 21:13 Profile Homepage #44
quote:
Originally written by Icshi:

I expect this produced even worse birth defects than Diethylstilbestrol.
I daresay the number of successful births due to this method was 0, yes.

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The Encyclopaedia Ermariana <-- Now a Wiki!
"Polaris leers down from the black vault, winking hideously like an insane watching eye which strives to convey some strange message, yet recalls nothing save that it once had a message to convey." --- HP Lovecraft.
"I single Aran out due to his nasty temperament, and his superior intellect." --- SupaNik
Posts: 8752 | Registered: Wednesday, May 14 2003 07:00
Ash Lael
E Equals MC What!!!!
Member # 5491
 written Thursday, September 1 2005 21:18 Profile Homepage #45
quote:
Originally written by Grape slime:

Congrads Thuryl! ^_^

EDIT: misspelt Thuryl
You astound me.

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Sex is easier than love.
Posts: 1861 | Registered: Friday, February 11 2005 08:00
Arancaytar
Law Bringer
Member # 2984
 written Thursday, September 1 2005 21:53 Profile Homepage #46
quote:
Originally written by Ash Lael:

quote:
Originally written by Grape slime:

Congrads Thuryl! ^_^

EDIT: misspelt Thuryl
You astound me.
EDID: Misbelt Congrats.

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The Encyclopaedia Ermariana <-- Now a Wiki!
"Polaris leers down from the black vault, winking hideously like an insane watching eye which strives to convey some strange message, yet recalls nothing save that it once had a message to convey." --- HP Lovecraft.
"I single Aran out due to his nasty temperament, and his superior intellect." --- SupaNik
Posts: 8752 | Registered: Wednesday, May 14 2003 07:00
Milla
Infiltrator
Member # 65
 written Friday, September 2 2005 01:24 Profile Homepage #47
Belated cheers for reaching 5000 posts.

And what is the interesting story behind 'Monkey Glands'?

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Also look at my sitehere
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Posts: 650 | Registered: Thursday, October 4 2001 07:00
Thuryl
...b10010b...
Member # 869
 written Friday, September 2 2005 01:44 Profile Homepage #48
quote:
Originally written by Milla:

And what is the interesting story behind 'Monkey Glands'?
Already posted it above:

http://www.ironycentral.com/cgi-bin/ubb/ubb/ultimatebb.php?ubb=get_topic;f=1;t=002793;p=2#000039

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Posts: 9973 | Registered: Saturday, March 30 2002 08:00
Milla
Infiltrator
Member # 65
 written Friday, September 2 2005 02:00 Profile Homepage #49
:o That teaches me to stop skimming through the posts.

[ Friday, September 02, 2005 02:02: Message edited by: Milla ]

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Posts: 650 | Registered: Thursday, October 4 2001 07:00

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